After miscarrying her cub, Serena is coldly blamed and abandoned by her mate Zane, who favors the scheming widow Quinn instead. Disillusioned, she breaks their bond and builds her own business with her pharmaceutical skills. Jealous Quinn frames Serena with wolfsbane, and Zane blindly condemns her to death. With the Supreme Alpha’s help, Serena exposes Quinn’s conspiracy in public. Crushed by regret, Zane begs for forgiveness, but Serena swears a blood oath to cut all ties. She grows into a powerful guild queen. Zane cripples himself in atonement yet is coldly rejected. He dies lonely in agony, while Serena adopts a wolf cub and leaves her miserable past behind for a brand-new life.